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Knee Pain · Osteoarthritis · GAE

Knee Pain Relief, Without Surgery. Knee pain when you climb the stairs? walk the dog? get out of the car? try to sleep? kneel in the garden? chase the grandkids? get off the couch? stand at work all day? dance at a wedding? travel through airports? get up off the floor? shop for groceries? take the downhill? sit through a movie? There's an option between shots and surgery.

Genicular Artery Embolization (GAE) is a minimally invasive, image-guided procedure that calms the inflamed blood vessels driving knee osteoarthritis pain — no incisions, no general anesthesia, home the same day. Performed by the board-certified interventional specialists of Apex Heart & Vascular, with 21 locations across New Jersey.

Walk out the same day Most insurance accepted Open 6 days a week Se habla español
Free · No obligation

Free Knee Pain Evaluation

Find out if GAE could help you — takes about 30 seconds. Our team will call to confirm a time.

By submitting, you agree that Apex Heart & Vascular may contact you by phone about scheduling. Your information stays confidential and is never sold.

Request received!

Our team will call you within one business day to schedule your knee evaluation. Want to talk sooner?

Call us at (973) 916-0002

Prefer to book online? Choose your own time →

0NJ Locations
0Patients Treated
0IAC Accreditations
AAAASFAccredited Facility
Watch · Straight from the doctor

Hear it from Dr. Shah.

Dr. Anuj Shah — Apex's founder and a board-certified interventional cardiologist — explains Genicular Artery Embolization in plain English: what it actually does inside the knee, who it helps, and why there's no incision.

  • How closing tiny abnormal vessels calms knee pain at its source
  • Who makes a strong candidate — and who doesn't
  • What the same-day recovery really looks like

Dr. Anuj Shah, MD — Founder, Apex Heart & Vascular Care

Apex physicians featured on

Living with knee pain

Does any of this sound familiar?

Knee osteoarthritis rarely announces itself. It shows up in small surrenders — the stairs you avoid, the walks you skip, the sleep you lose. These are the moments patients tell us about. Tap any that sounds like you.

Interactive · Free · 60 seconds

The 60-Second Knee Check

Answer five quick questions about your knee. We'll show you how closely your situation matches the patients who benefit most from GAE — instantly.

Step 1 of 6

Where does your knee hurt most?

Tap the diagram or the options — choose every area that applies.

A B C D BACK OF KNEE E

Front view of a right knee, as if you were looking down at your own — inner side on your left. Tap every area that hurts.

How long has this knee been hurting?

Pick the closest answer.

On a typical day, how bad is the pain?

Slide to rate it — 0 is no pain, 10 is the worst imaginable.

5 Moderate
0 · No pain10 · Worst imaginable

What have you already tried?

Select all that apply — this matters more than you'd think.

What is your knee costing you?

Select everything the pain interferes with.

Your Knee Check is ready.

Tell us where to send it — our care team will also review your answers personally, free of charge.

What you'll get

Your candidacy result on screen right now, plus a call from our knee team within one business day to walk through it and — if it's a fit — reserve an evaluation at whichever of our 21 offices is closest to you.

Your match score is calculated. Unlock it on the right.

We'll call about scheduling only — your answers stay confidential.

Multiple answers welcome
Femoral artery Descendinggenicular artery Superior medialgenicular artery Inferior medialgenicular artery Abnormal vessels —the target of GAE Popliteal arteryruns behind the knee Superior lateralgenicular artery Inferior lateralgenicular artery Anterior tibial artery

The genicular artery network of the right knee. The pulsing cluster at the inner joint line is the web of abnormal vessels that forms with osteoarthritis — the exact target GAE closes down.

The science, in plain English

Why your knee still hurts — even after the shots.

Osteoarthritis isn't just "worn cartilage." As the joint wears, the lining becomes chronically inflamed — and your body grows a web of abnormal little blood vessels to feed that inflammation. New nerve endings grow right alongside them. That's the loop that keeps hurting no matter how many injections you get.

  1. Cartilage wears downThe cushioning in the joint thins, and the lining (synovium) becomes irritated and inflamed.
  2. Abnormal vessels move inInflammation triggers new, abnormal blood vessels — which deliver even more inflammatory cells to the knee.
  3. Nerves follow the vesselsPain fibers grow along the new vessels. The knee becomes tender, achy, and swollen around the clock.
  4. GAE breaks the loopGenicular Artery Embolization closes down those abnormal vessels with microscopic particles — starving the inflammation while healthy circulation is preserved.
Where GAE fits

The treatment gap nobody told you about.

You've probably tried half of these already. Tap any of them and see, side by side, why it kept falling short — and what GAE does differently.

What you've been offered

Cortisone shots

What it does
A steroid temporarily quiets the inflamed joint lining.
Relief typically lasts
Weeks to a few months — often less each time.
The catch
Repeated shots have been linked to faster cartilage thinning.
The missing step

Genicular Artery Embolization

What it does
Closes the abnormal vessels feeding the inflammation — treating the cause, not masking the symptom.
Relief typically lasts
2–3 years in published studies — and it can be safely repeated.
The catch
A pinhole and a same-day visit. No incisions, nothing implanted — and surgery stays on the table if you ever want it.
Am I a candidate? →

GAE is for the in-between knee: too painful for another round of shots that barely help, but you're not ready — or not able — to have the joint replaced. Typical candidates are adults 40+ with osteoarthritis on imaging and pain that has lasted 3+ months despite conservative care.

Outcomes & evidence

The numbers behind the procedure.

GAE isn't new, and it isn't a hunch. It has been studied for over a decade in peer-reviewed trials around the world — including randomized, sham-controlled studies. Here's what the published literature reports for well-selected knee osteoarthritis patients.

0%Report meaningful reliefAcross published GAE trials in knee osteoarthritis
~0%Average pain-score dropTypical VAS pain reduction at 6 months
2–3 yrsTypical relief durationWith the option to safely repeat the procedure
<0%Major complication rateLower than surgical alternatives; most side effects are mild and temporary
0%Technical successIn the U.S. pivotal trial — every procedure completed as planned
0+Patients studiedIn published GAE research worldwide
0+Peer-reviewed studiesAcross the U.S., Europe and Asia
0+Years of clinical useSince the first published GAE series

Backed by rigorous science

Randomized, sham-controlled trials

In blinded studies, patients who received real GAE reported significantly greater pain relief than patients who received a placebo procedure — the strongest test in medicine.

FDA-supervised U.S. research

American pivotal trials were conducted under FDA Investigational Device Exemption oversight — the same rigorous pathway used to evaluate new cardiac devices.

Adopted worldwide

Pioneered in Japan and now performed and studied at leading academic medical centers across four continents — with results replicated again and again.

…and the hard truths about the old playbook

15–20%of total knee replacement patients report persistent pain after surgery
6–12 wkstypical cortisone relief — and repeated shots have been linked to faster cartilage loss (JAMA)
0 benefitover sham surgery for arthroscopic "clean-outs" in arthritis, in landmark trials (NEJM)

Figures reflect ranges reported across published clinical literature — including randomized controlled trials — for appropriately selected patients. GAE does not regrow cartilage, and individual results vary; candidacy is confirmed at your in-person evaluation.

Benefits & highlights

The GAE difference, at a glance.

Two lists tell the whole story — what disappears from the experience, and what you get in its place.

What you avoid — entirely

The parts of knee surgery patients dread most simply aren't part of this procedure.

  • No incisionsA pinhole closed with a small bandage — nothing to heal from
  • No stitches or implantsNothing is cut, and nothing artificial is left behind
  • No shots into the jointNo cortisone, no gel — the knee itself is never injected
  • No general anesthesiaLight sedation with local numbing; you breathe on your own
  • No hospital stayNo operating room, no overnight bag, no rehab facility
  • No months of rehabMost patients are back to light activity within days
  • No guessworkLive imaging maps your arteries so healthy circulation is preserved

What you get instead

A short, precise, image-guided procedure — with relief that holds.

  • A 45–90 minute procedureStart to finish — shorter than a ball game
  • Home & moving the same dayWalk in, walk out — and sleep in your own bed tonight
  • Minimal discomfortTypically mild soreness for a few days, managed with OTC medicine
  • Relief that lastsOften 2–3 years in published studies
  • A repeatable optionIf pain returns years later, GAE can safely be done again
  • Treatment of the causeCloses the abnormal vessels feeding the inflammation — not just the pain signal
  • Coverage by most insuranceWhen medical criteria are met — verified before your visit
Side by side

How GAE stacks up.

Six paths, eight honest questions — all on one screen. Tap any column to spotlight it.

★ The missing stepGAEat Apex Cortisone & gelinjections PRP & stem cellsbiologics PT & bracesconservative Arthroscopykeyhole surgery Knee replacementpartial or total
AnesthesiaLocal + sedationNone / localNone / localNoneGeneralGeneral
IncisionPinholeNeedleNeedleNone2–3 cutsSurgical
Time awaySame-day homeMinutesMinutesOngoingDays–weeksWeeks–months
Relief lasts2–3 yearsWeeks–monthsUnclearWhile you keep it upLittle for OALong-term
Treats the cause?YesNoUnprovenNoNoReplaces it
Repeatable?YesLimitedAt full costYesRarely helpsComplex revision
Usually covered?YesYesRarelyYesYesYes
Surgery still possible after?YesYesYesYesMostlyIt is the surgery

Every knee is different — your Apex physician will tell you honestly which path fits yours, even when the answer isn't a procedure.

Your questions, answered

Everything patients ask us about GAE.

Straight answers to the questions we hear every day. Tap any question to expand it.

GAE is a minimally invasive, image-guided procedure for knee osteoarthritis pain. Through a pinhole in the wrist or upper thigh, a thin catheter is guided to the genicular arteries around your knee. Your physician then releases microscopic particles that close down the abnormal blood vessels feeding the inflammation in the joint lining — while healthy circulation is preserved. Less inflammation means less pain, typically beginning within 2–4 weeks.
No — GAE is not surgery. There are no incisions, no stitches, and no implants. You'll be awake but relaxed under local anesthesia with light sedation, similar to a colonoscopy. Most patients walk out the same day with a small bandage.
Typical candidates are adults 40 and older with knee osteoarthritis confirmed on imaging, whose pain has lasted 3+ months despite conservative care (medication, PT, injections). GAE is also an option for people who want to delay a knee replacement, aren't healthy enough for major surgery — or who have persistent pain after a knee replacement. Your Apex physician confirms candidacy at an in-person evaluation with imaging.
Possibly, yes. Persistent pain or recurrent swelling after a knee replacement is often driven by inflamed, abnormal blood vessels around the implant — and embolization has been studied specifically for this problem. If your surgeon has ruled out infection or a mechanical issue with the implant, a GAE evaluation is a reasonable next step.
No, and we won't tell you otherwise. GAE does not regrow cartilage — it treats the inflammation that drives most of the day-to-day pain. In published studies, relief typically lasts 2–3 years and the procedure can be safely repeated. For many patients that means years of activity without surgery; for others it's a bridge that lets them arrive at an eventual replacement stronger and on their own timeline.
You'll walk out the same day. Expect mild soreness or aching in the knee for a few days as the inflammation settles — most patients are back to desk work the next day and light activity within a few days. Meaningful pain relief typically begins around weeks 2–4 and continues improving through month 3.
GAE has a strong safety profile. The most common side effects are temporary: mild knee soreness, bruising at the pinhole, or small patches of skin discoloration near the knee that fade over weeks. Major complications are rare — reported at under 1% in published series, lower than surgical alternatives. Your physician reviews your personal risk profile before anything is scheduled.
Coverage varies by plan, and this is exactly what our team handles for you: we verify your benefits before your first visit and explain any costs up front — no surprises. Apex accepts most major commercial, Medicare, and Medicaid HMO plans. Not sure about yours? Call us at (973) 916-0002 and we'll check it for you.
Because GAE is a blood-vessel procedure — and navigating arteries with catheters is exactly what interventional cardiologists and vascular specialists do all day, on the most demanding vessels in the body. Apex physicians bring thousands of image-guided procedures' worth of experience, four IAC accreditations, and an AAAASF-certified facility to your knee.
Usually within the same week. With 21 locations across North Jersey and hours 6 days a week — including Saturdays — there's almost always a convenient opening near you. Call us at (973) 916-0002 or request your evaluation on this page and we'll find the earliest slot at your nearest office.

This page is for education and is not a substitute for medical advice, diagnosis, or treatment. Always consult a qualified physician about your specific condition.

Pain after knee replacement

Had the surgery — and it still hurts?

You did everything right. You had the replacement, you did the rehab — and the knee still aches, swells, or keeps you up at night. You're not imagining it, and you're not alone.

Persistent pain after knee replacement is often driven by the same abnormal, inflamed blood vessels GAE was designed to treat. Embolization has been studied specifically for ongoing pain and recurrent swelling after knee replacement — without another operation.

15–20% of knee replacement patients report persistent pain after surgery — many are told nothing more can be done. GAE offers a studied, incision-free option.
Knee patient stories

In their own words, after GAE.

★★★★★4.9 / 5across Google, Healthgrades & Zocdoc
★★★★★
I was three weeks out from a knee replacement I was dreading. After GAE at Apex I cancelled the surgery — I'm back to walking my dog every morning.
Knee OA patient · 67
★★★★★
Two years after my knee replacement it still ached every night. Apex found the inflamed vessels and treated them — I finally sleep through the night.
Post-replacement patient · 71
★★★★★
Cortisone was down to helping for two weeks at a time. GAE gave me my stairs back — I walked out the same afternoon with a Band-Aid.
Knee OA patient · 58
★★★★★
Todo el equipo habla español y me explicaron cada paso. El procedimiento fue rápido y volví a caminar sin dolor. Los recomiendo con confianza.
Paciente de rodilla · 63
★★★★★
I was three weeks out from a knee replacement I was dreading. After GAE at Apex I cancelled the surgery — I'm back to walking my dog every morning.
Knee OA patient · 67
★★★★★
Two years after my knee replacement it still ached every night. Apex found the inflamed vessels and treated them — I finally sleep through the night.
Post-replacement patient · 71
★★★★★
Cortisone was down to helping for two weeks at a time. GAE gave me my stairs back — I walked out the same afternoon with a Band-Aid.
Knee OA patient · 58
★★★★★
Todo el equipo habla español y me explicaron cada paso. El procedimiento fue rápido y volví a caminar sin dolor. Los recomiendo con confianza.
Paciente de rodilla · 63
★★★★★
I was three weeks out from a knee replacement I was dreading. After GAE at Apex I cancelled the surgery — I'm back to walking my dog every morning.
Knee OA patient · 67
★★★★★
Two years after my knee replacement it still ached every night. Apex found the inflamed vessels and treated them — I finally sleep through the night.
Post-replacement patient · 71
★★★★★
Cortisone was down to helping for two weeks at a time. GAE gave me my stairs back — I walked out the same afternoon with a Band-Aid.
Knee OA patient · 58
★★★★★
Todo el equipo habla español y me explicaron cada paso. El procedimiento fue rápido y volví a caminar sin dolor. Los recomiendo con confianza.
Paciente de rodilla · 63

Patient stories illustrate typical outcomes. Individual results vary based on condition, severity, and follow-up care.

Dr. Anuj Shah, founder of Apex Heart & Vascular
Dr. Anuj Shah, MDFounder · Interventional Cardiology
Apex interventional team performing an image-guided procedure
Interventional TeamImage-guided procedures
Apex care team
Care CoordinatorsEnglish · Español & more
Meet your knee team

Catheter experts. Now for your knee.

GAE is a blood-vessel procedure — so it belongs in the hands of physicians who navigate arteries for a living. Apex's board-certified interventional cardiologists and vascular specialists have performed thousands of image-guided procedures on the body's most unforgiving vessels. Your knee gets that same precision.

30,000+Patients treated across Apex
21New Jersey locations
6Days a week, incl. Saturdays
"Apex didn't try to push me into a surgery I didn't want. They explained GAE, treated me with respect, and gave me back the ability to walk pain-free."Verified Apex patient
Accredited & recognized

Independently accredited.
Nationally recognized.

Accreditation isn't marketing — it's earned. Apex holds four separate IAC accreditations plus AAAASF surgical certification, awarded only after independent medical experts review our physicians, equipment, imaging protocols and safety record — and re-verified every three years. It's outside proof that the care you receive here meets the highest national standards.

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IAC Accredited
Four separate Intersocietal Accreditation Commission accreditations — a distinction held by very few practices in New Jersey.
AAAASF
Our surgical facility meets the rigorous safety and quality standards of the AAAASF.
NJ Top Docs
Recognized among New Jersey's top physicians for patient care.
Hospital Network
Privileges at every major local hospital — seamless, connected care if you ever need it.
Coverage made easy

Great care shouldn't be complicated.

We accept most major commercial, Medicare & Medicaid HMO plans — and our team will check your benefits before your first visit. Not sure? Call (973) 916-0002 and we'll verify it for you.

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21 locations. One phone number.

Essex · Bergen · Passaic · Hudson · Union · Morris — wherever you are in North Jersey, there's an Apex office nearby, open 6 days a week. Find yours on the map below.

Call us at (973) 916-0002
One last step

Your knees have carried you this far.
Now let us carry some of the weight.

A one-hour evaluation is all it takes to know whether GAE fits your knee. No pressure, no obligation — just an honest answer from a specialist who does this every day.

Takes 30 seconds

Request your knee evaluation

We'll call you within one business day to schedule at your nearest office.

By submitting, you agree that Apex Heart & Vascular may contact you by phone about scheduling. Your information stays confidential and is never sold.

Request received!

Our team will call you within one business day. Talk to someone sooner at (973) 916-0002.